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Parkinson’s disease is a progressive disease that causes damage to parts of the brain, especially the substantia nigra. It is the most common motor brain condition.
It remains unclear whether hypoperfusion volume elevates the risk of hemorrhagic transformation (HT) after endovascular thrombectomy (EVT) in patients with acute ischemic stroke (AIS). This study aims to inves...
Parkinson’s disease (PD), a prevalent neurodegenerative disorder in the aging population, poses significant challenges in unraveling its pathogenesis and progression. A key area of investigation is the disrupt...
This study aims to investigate the causal relationship between Mitochondrial DNA (mtDNA) copy number and several common neurodegenerative diseases (NDs).
This review aims to comprehensively examine the role of bilirubin in predicting severity and adverse clinical outcomes in patients with acute ischemic stroke (AIS).
Sub-Saharan Africans and Afro-Americans face 2-to-8 times higher risk of dementia compared to Caucasians, with Nigerian people being the highest population-at-risk. Adding to this challenge, their unique lipid...
Traumatic brain injury (TBI) causes major societal burden and may negatively influence an individual’s health-related quality of life (HRQoL). Personality factors have been linked to persistent post-concussion...
Sleep disturbances are common in patients with chronic migraine, yet the clinical predictors of sleep quality in this population remain unclear. This study aimed to explore the relationship between sleep quali...
Butylphthalide has shown significant potential in the treatment of ischemic stroke, but its precise mechanisms of action remain unclear. Long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) play crucial r...
Alzheimer’s Disease (AD) is marked by intricate immunological alterations, including the dysregulation of interleukin signaling. This study investigates the differential expression and potential roles of inter...
Stroke is a cerebrovascular disease that is the main cause of death and disability worldwide. Hypoxia is a major factor that causes neuronal damage and even cellular death. However, the mechanism and therapeut...
Primary headache associate with sexual activity (PHASA) is a relatively rare clinical condition and characterized by thunderclap headache exclusively triggered by sexual activity. The suggested involvement of ...
Aneurysmal subarachnoid hemorrhage (aSAH) patients usually suffer poor survival outcome and severe morbidity. Evaluating prognosis of aSAH patients in acute phase is essential for physicians to make suitable t...
To assess safety and efficacy of endovascular treatment (EVT) in acute ischemic stroke (AIS)patients selected by ASPECTS within 6–24 h after onset.
Stiff Person Syndrome (SPS) is a rare autoimmune neurological disorder characterized by progressive muscle rigidity and painful spasms. Standard treatments often yield variable responses, particularly in sever...
Stroke-associated pneumonia (SAP) is relevant to the poor functional outcomes of patients with spontaneous intracerebral hemorrhage (SICH). It is unclear if the triglyceride (TG) to high-density lipoprotein ch...
Multiple sclerosis (MS) is a chronic neuroinflammatory disorder that can present with clinical and radiological features indistinguishable from a central nervous system (CNS) tumor. Previous studies suggest th...
Chronic low back pain is a global health issue that leads to disability and significant economic costs. However, it has received limited attention in low- and middle-income countries. This study aimed to deter...
Autonomic symptoms are mandatory for making the diagnosis of a trigemino-autonomic cephalalgia (TAC). These symptoms can occasionally also occur in migraine and facial pain disorders. This leads to the questio...
Promoting dietary diversity (DD), which refers to the variety or the number of different food groups that people eat over the time given, is important for brain health maintenance and may be beneficial for inh...
Drug-resistant epilepsy (DRE) is a significant global public health challenge affecting people with epilepsy (PWE). Despite the availability of multiple drug therapies, a significant number of PWE with DRE con...
Behçet’s disease (BD) is a multi-system recurrent inflammatory disease. Neuro-Behçet’s disease (NBD), as a severe and rare manifestation of BD, is frequently misdiagnosed in its early stages. Pediatric NBD pos...
This study aimed to evaluate the safety and feasibility of carotid artery stenting (CAS) using a 6 F guiding catheter via right distal radial artery access.
Meningiomas are tumors that originate from non-neuroepithelial progenitor cells, meningothelial cells and the arachnoid cap cells, thus they usually appear with attachment to the dura mater. But sylvian fissur...
Acute intermittent porphyria (AIP) is a rare but treatable disease. COVID-19 has various possible complications including posterior reversible encephalopathy syndrome (PRES). COVID-19 was reported to trigger a...
Multiple sclerosis (MS) is a chronic disease that presents individuals with various caregiving challenges, making their empowerment based on their real needs essential. The aim of this study was to determine t...
Pyoderma Gangrenosum (PG) is often considered an immune-mediated disease. Up to 50% of PG cases - a rare, non-infectious inflammatory skin disease characterized by painful necrotic ulcers -are associated with ...
MS is characterized by persistent central nervous system (CNS) inflammation. Investigating the CNS-compartmentalized inflammation associated with progressive MS could uncover new biomarkers and therapeutic tar...
Lifestyle measures in addition to pharmacotherapy are recommended to optimise stroke secondary prevention. Adopting and sustaining good health behaviours after stroke necessitates ongoing motivation, influence...
Growth-associated protein 43 (GAP-43) is a key protein involved in neuronal growth and synaptic plasticity. Alterations in GAP-43 levels have been associated with Alzheimer’s Disease (AD), potentially reflecti...
Epilepsy is a common condition that affects the brain and causes frequent seizures. Impaired brain biology is the world’s fastest-growing brain disorder, and exposure to environmental pollutants is the leading...
The Correction to this article has been published in BMC Neurology 2025 25:210
Choosing migraine prevention medications often involves trial and error. Operations research methodologies, however, allow us to derive a mathematically optimum way to conduct such trial and error processes.
Previous results on the association between HDL (high-density lipoprotein cholesterol) levels and intracranial aneurysm (IA) rupture were controversial. We aimed to investigate the association between HDL leve...
Ischemic stroke is a common chronic disease worldwide and is correlated with a high disability rate. Sarcopenia is considered a key factor in the disablement process. Limited evidence of sarcopenia in acute is...
Social cognitive impairments often occur in patients with various neurological disorders that involve brain damage, such as traumatic brain injury, stroke, brain tumours, and multiple sclerosis. Patients with ...
Leigh syndrome (LS) is an inherited form of mitochondrial encephalopathy associated with various gene mutations of the oxidative phosphorylation system, typically occurring in infancy or early childhood and re...
To report a case of Corynebacterium striatum meningitis and conduct a comprehensive literature review to determine the clinical presentation, microbiology, and treatment approaches for these patients.
This investigation is designed to evaluate the effects of rTMS and its varying stimulation parameters and target sites on the therapeutic outcomes for post-stroke lower limb motor impairment and balance, with ...
The original article was published in BMC Neurology 2025 25:85
Optic neuritis (ON) is an inflammatory optic neuropathy characterized by acute vision loss. Primary anti-PLA2R-positive membranous nephropathy, an autoimmune disease, has been reported to be related to neurolo...
Autism spectrum disorder (ASD) is a neurodevelopmental disorder primarily impacting social communication and behavior. The prevalence of ASD has been rapidly increasing, leading to a corresponding rise in the ...
Brain-derived neurotrophic factor (BDNF) is among the modulators associated with cognition and sleep that play a role in sleep disorders. This study aimed at investigating the effects of chronic sleep deprivat...
Apart from the limited evidence of the effects of very early exercise (VEE) on clinical outcomes (COs) in stroke, better knowledge is required to understand the cellular action induced by VEE. This study inves...
The impact of hydrocephalus on the emotional, cognitive, and social health of children is frequently overlooked when measuring clinical outcomes in children with hydrocephalus. The aim of this study was to det...
The clinical features of neuromyelitis optica spectrum disorder (NMOSD) predominantly include optic neuritis and myelitis, among other symptoms. A greater level of disability during the acute phase typically s...
Based on the data of Parkinson’s disease patients in Xinjiang, China, to explore the clinical application value of blood biomarkers in diagnosing Parkinson’s disease patients.
The second most common cause of death and disability worldwide is stroke. Drug-related problems (DRPs) can arise during any step of the medication process, whether it involves prescribing, transcribing, dispen...
Hemorrhagic stroke has a high mortality and disability rate. Among them, intraventricular hemorrhage (IVH) is an important factor leading to adverse outcomes. IVH can induce acute obstructive hydrocephalus and...
Acute transient myopia with shallowing of the anterior chamber is a rare idiosyncratic response to many systemic and topical medications, including topiramate. Several such cases have been reported in the past...
The glymphatic system, a waste clearance pathway, has been implicated in several neurological conditions associated with neuroinflammation. COVID-19 associated neurocognitive impairment, part of the post-acute...
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