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  1. Entacapone has been widely used in the treatment of moderate to advanced Parkinson’s disease (PD), and its efficacy for motor symptoms has been well-known from several clinical trials and long-term clinical us...

    Authors: Dongjuan Xu, Yuan Fang, Mengmeng Hu, Yilei Shen, Hongfei Li, Lianyan Wei and Juping He
    Citation: BMC Neurology 2025 25:116
    Content type: Research Published on:

  2. Post-stroke delirium, a frequent and significant complication of stroke, manifests as a sudden onset of confusion, altered consciousness, and cognitive decline. Various factors contribute to its occurrence, in...

    Authors: Beruk Ketema, Getahun Mengistu, Dereje Melka, Yared Zenebe, Mehila Zebenigus and Feryat Leul
    Citation: BMC Neurology 2025 25:114
    Content type: Research Published on:

  4. Refractory intracranial hypertension is a condition characterized by persistently elevated intracranial pressure that does not respond to conventional treatments. Diagnosis and management typically involve a c...

    Authors: Qihan Zhang, Yaqin Gu, Yang Hua, Peng Zhang, Jian Chen, Xin Qu, Xunming Ji and Jiangang Duan
    Citation: BMC Neurology 2025 25:110
    Content type: Case Report Published on:

  6. Migraine is a highly prevalent and disabling condition, not only due to its painful symptoms but also because of its significant impact on mental health and cognitive functioning, leading to a considerable det...

    Authors: Diana Carolina López-Medina, Alejandra Arboleda-Ramírez, Sara Ríos-Díaz, Renato Zambrano-Cruz, Andrés Arboleda-Jaramillo, Cristian Betancur-Henao and Marcela Henao-Pérez
    Citation: BMC Neurology 2025 25:108
    Content type: Research Published on:

  7. Many people with Multiple Sclerosis (MS) in Europe face limited treatment and care access. Research on the challenges faced by people who do not access specialized MS care and treatment is limited, leaving a g...

    Authors: Agata Beczek, S. G. Roikjær, C. Simonÿ, E. M. Landt, L. Storr, M. Dahl and M. Beck
    Citation: BMC Neurology 2025 25:107
    Content type: Research Published on:

  9. The Cardiometabolic Index (CMI), a novel metabolic marker, has been associated with various metabolic diseases in previous studies. However, its relationship with stroke risk remains underexplored. This study ...

    Authors: Yibo Yang, ZhenKun Xiao, Jing Teng, Hailong Zhong, Yonghong Duan, Min Zhou, Bing Wang and Aihua Liu
    Citation: BMC Neurology 2025 25:105
    Content type: Research Published on:

  10. Post-stroke depression (PSD) refers to a depressive state that appears after stroke onset and is one of the most common complications in ischemic stroke patients. The occurrence of PSD exacerbates the risk of ...

    Authors: AiNi Xiao, RuiYang Wang, CongJie Liu and XiangYu Wang
    Citation: BMC Neurology 2025 25:104
    Content type: Research Published on:

  11. Migraine is associated with various types of stigma. This study aims to evaluate stigmatizing attitudes towards people with migraine by people without active migraine.

    Authors: Robert E. Shapiro, Lars Viktrup, Eva Jolanda Muenzel, Dawn C. Buse, Anthony J. Zagar, Sait Ashina, Susan Hutchinson, Robert A. Nicholson and Richard B. Lipton
    Citation: BMC Neurology 2025 25:103
    Content type: Research Published on:

  13. Multiple Sclerosis (MS) is a long-term condition affecting the central nervous system that typically manifests in young adults. Stigma poses significant psychosocial challenges for patients with MS, negatively...

    Authors: Nazgol Behgam, Amirhossein Sahraian, Zahra Ebadi, Shima Jahani and Mohammad Ali Sahraian
    Citation: BMC Neurology 2025 25:101
    Content type: Research Published on:

  14. To validate JLK-LVO, a software detecting large vessel occlusion (LVO) on computed tomography angiography (CTA), within a multicenter dataset.

    Authors: Kyu Sun Yum, Jong-Won Chung, Sue Young Ha, Kwang-Yeol Park, Dong-Ick Shin, Hong-Kyun Park, Yong-Jin Cho, Keun-Sik Hong, Jae Guk Kim, Soo Joo Lee, Joon-Tae Kim, Woo-Keun Seo, Oh Young Bang, Gyeong-Moon Kim, Myungjae Lee, Dongmin Kim…
    Citation: BMC Neurology 2025 25:100
    Content type: Research Published on:

  16. Previous studies have suggested a possible link between normal pressure hydrocephalus (NPH) and immune factors, but the causal relationship between NPH and Baff-R expression on immune cells remains enigmatic. ...

    Authors: Wencai Wang, Luyao Ma, Menghao Liu, Yongqiang Zhao, Wei Ye and Xianfeng Li
    Citation: BMC Neurology 2025 25:98
    Content type: Research Published on:

  17. In the face of the global COVID-19 pandemic, the need arose to investigate potential complications associated with SARS-CoV-2, including the risk of stroke.

    Authors: Andreza Maria Luzia Baldo de Souza, Enoque Fernandes de Araújo, Nelson Carvas Junior, Augusto Cesar Sousa Raimundo, Antonio Carlos Pereira and Marcelo de Castro Meneghim
    Citation: BMC Neurology 2025 25:97
    Content type: Systematic Review Published on:

  19. The purpose of the present study is to investigate the association between imaging characteristics and progressive infarction (PI) in patients with anterior circulation single subcortical infarction (ACSSI).

    Authors: Liangbin Dong, Xiaocheng Mao, Kaiyan Jiang, Zubing Xu, Shumeng Li, Jincai Tang, Xiaobing Li, Qin Huang and Jing Lin
    Citation: BMC Neurology 2025 25:95
    Content type: Research Published on:

  20. Traumatic brain injuries (TBIs) are characterized by myriad comorbidities that affect the functioning of the affected individuals. The comorbidities that TBI subjects experience span a wide range, ranging from...

    Authors: Kaustav Mehta and Shyam Kumar Sudhakar
    Citation: BMC Neurology 2025 25:94
    Content type: Research Published on:

  21. Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs worldwide, which is used to treat migraines, bipolar disorder, and anxiety. However, VPA is associated with a wide range of side eff...

    Authors: Shada Abutaleb, Eyad Mallah, Luay Abu-Qatouseh, Ahmad Abu-awwad, Kenza Mansoor, Sarah Khallad, Khaled W. Omari, Omar Mouhtady and Tawfiq Arafat
    Citation: BMC Neurology 2025 25:93
    Content type: Research Published on:

  22. The presence of early venous filling (EVF) post-mechanical thrombectomy (MT) in acute ischemic stroke (AIS) patients has been observed, yet its prognostic value for clinical outcomes remains underexplored. Thi...

    Authors: Jiaxin Han, Yixuan Wu, Zihan Wang, Jianfeng Han, Guogang Luo and Kang Huo
    Citation: BMC Neurology 2025 25:92
    Content type: Research Published on:

  23. This study intends to investigate the connection between non-contrast computed tomography (NCCT) imaging findings and neurological function scores in patients with intracerebral hemorrhage (ICH) in a long foll...

    Authors: Rong Deng, Chuyue Wu, Lina Zhang, Jing Wang, Jing Guo, Zhenjie Yang, Lei He and Shengli Chen
    Citation: BMC Neurology 2025 25:91
    Content type: Research Published on:

  24. Inflammatory mechanisms play a significant role in ischemic stroke. Peripheral neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), systemic infla...

    Authors: Yiyuan Xu and Yanyan Liu
    Citation: BMC Neurology 2025 25:90
    Content type: Research Published on:

  25. Patients with diffuse axonal injury (DAI) are often plagued by sequelae, and the current indicators for predicting long-term neurological function are not accurate enough. Our previous studies have found that ...

    Authors: Weiliang Chen, Jiayi Wu, Shengwen Li, Chunyu Yao, Rui Chen, Wen Su and Guanjun Wang
    Citation: BMC Neurology 2025 25:89
    Content type: Research Published on:

  26. Previous studies have examined the various outcomes of expressive writing intervention in different populations. The purpose of this study was to evaluate the effect of expressive writing on the sexual self-co...

    Authors: Malihe Mohammadzade Sabbaghi, Leila Amini, Seyed Massood Nabavi, Naiemeh Seyedfatemi and Hamid Haghani
    Citation: BMC Neurology 2025 25:88
    Content type: Research Published on:

  27. Currently, there are limited reports, both nationally and internationally, regarding Guillain-Barré Syndrome (GBS) that manifests solely with isolated sensory impairment. This study aims to explore the epidemi...

    Authors: Songyan Liu, Hong Chu, Bin Peng, Yanping Zeng, Jia Liu, Zuneng Lu and Chao Weng
    Citation: BMC Neurology 2025 25:87
    Content type: Research Published on:

  29. Multiple sclerosis is an inflammatory demyelinating autoimmune disease of the central nervous system. Studies conducted in recent years point to an increase in its prevalence and a change in the age profile of...

    Authors: Pedro Oliva-Nacarino, Marina Simal Antuña, Carmen Santos Varela, Javier Villafani Echazú, Jessica Fernández Domínguez, Raquel García Rodríguez, Agustín Oterino Durán, Patricia Suarez Santos and Miguel Ángel Llaneza González
    Citation: BMC Neurology 2025 25:85
    Content type: Research Published on:

    The Correction to this article has been published in BMC Neurology 2025 25:125

  30. Epilepsy is a severe neurological disorder characterized by persistent seizures and, in some patients, associated neurobiological, cognitive, and psychosocial consequences. It is influenced by various genetic ...

    Authors: Xudong Zhang, Yuhao Xu, Zehan Wu and Xiang Zou
    Citation: BMC Neurology 2025 25:84
    Content type: Research Published on:

  32. Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disorder with an increasing incidence rate. Despite advances in ALS research over the years, the precise etiology and pathogenic mech...

    Authors: Chuan Lu, Xiao-xiao Huang, Ming Huang, Chaoning Liu and Jianwen Xu
    Citation: BMC Neurology 2025 25:82
    Content type: Research Published on:

  33. Exercise in healthy individuals is associated with a hypercoagulable phase, leading to a temporary increase in clot mass and strength, which are controlled by an effective fibrinolytic system. Conversely, peop...

    Authors: J. C. Zaldua, O. Watson, D. J. Gregoire, S. Pillai, Y. Hellsten, K. Hawkins and P. A. Evans
    Citation: BMC Neurology 2025 25:81
    Content type: Research Published on:

  35. Myasthenic crisis (MC) refers to rapid deterioration of myasthenia gravis (MG), affecting lung and bulbar muscles and causing breathing difficulties. Currently, efgartigimod has shown good therapeutic effects ...

    Authors: Fangyi Shi, Rong Lai, Li Feng, Hongyan Zhou, Xunsha Sun, Cunzhou Shen, Jiezhen Feng, Zhilong Xu, Haiyan Wang and Huiyu Feng
    Citation: BMC Neurology 2025 25:79
    Content type: Research Published on:

  37. Warfarin is the most commonly used oral anticoagulant drug in clinical practice due to its effective anticoagulant effect and low cost. Warfarin plays a crucial role in the anticoagulant treatment of patients ...

    Authors: Xiaoyan Du, Peng Zhang, Linhai Hu, Qiu Chen, Shuang Cheng, Xinyu Qiu and Libo Zhao
    Citation: BMC Neurology 2025 25:77
    Content type: Case Report Published on:

  39. The primary symptoms in the early stages of anti-NMDA receptor encephalitis are psychiatric manifestations, making it difficult to distinguish from psychiatric disorders. While anti-NMDA receptor encephalitis ...

    Authors: Risa Hirata, Hisashi Wada, Kazunori Yamamoto, Yuji Sogi, Hiroto Muzuta, Yu Isaka and Michitaka Funayama
    Citation: BMC Neurology 2025 25:75
    Content type: Case Report Published on:

  40. Ischemic stroke is a significant public health concern, particularly in Eastern Europe, where the burden remains high. This study aims to evaluate the trends and burden of ischemic stroke in Eastern Europe fro...

    Authors: Jingyao Xu, Shuai Hou, Zimeng Chen, Yong Liu, Xia Deng, Chunping Wang, Shijie Liu and Yanqiang Wang
    Citation: BMC Neurology 2025 25:74
    Content type: Research Published on:

  41. The Circle of Willis (CoW) is a crucial cerebral arterial structure that facilitates collateral blood flow to the brain. Anatomical variations within the CoW are prevalent and can have significant clinical imp...

    Authors: Hashime Meketa Negatie, Molla Asnake Kebede, Alemayehu Dagne Abate, Solyana Haileselassie Admassie, Adugnaw Bogale Worku, Hanan Tofiek Ahmed, Yohanes Yoseph Mesfine and Melkamu Mitikie Melak
    Citation: BMC Neurology 2025 25:73
    Content type: Research Published on:

  42. Guillain-Barré syndrome (GBS) is a group of immune-mediated peripheral neuropathies that causes acute flaccid paralysis. The global incidence of GBS was 0.6-4/100 000, and the incidence in China was 0.698/100 ...

    Authors: Feng Guo, Qin-Yuan Yao, Xiao-Hong Wu, Hui-Xia Guo, Xiao-Lin Su, Jin-Fang Zhou, Li-Jie Ren and Yan-Xia Zhou
    Citation: BMC Neurology 2025 25:72
    Content type: Research Published on:

  43. Hydrocarbon exposure, including polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs), is increasingly linked to vascular dysfunction and stroke, a leading cause of morbidity and mortal...

    Authors: Muhammed Shabil, Abhay M. Gaidhane, Nasir Vadia, Soumya V. Menon, Kattela Chennakesavulu, Rajashree Panigrahi, Ganesh Bushi, Diptismita Jena, Anju Rani, Sanjit Sah, Mahendra Singh, Prakasini Satapathy, Khang Wen Goh and Nosaibah Razaqi
    Citation: BMC Neurology 2025 25:71
    Content type: Systematic Review Published on:

  44. The lumbar sympathetic nerve block stands as a pivotal approach in managing complex regional pain syndrome (CRPS) in the lower limbs. Retroperitoneal hemorrhage is an extremely rare and severe complication of ...

    Authors: Yan Bai, Xinqiao Zhou, Lingqing Zeng, Xiaokai Zhou, Zhuqing Rao, Cunming Liu, Yinbing Pan and Xiaodi Sun
    Citation: BMC Neurology 2025 25:70
    Content type: Case Report Published on:

  45. To evaluate the potential of two large language models (LLMs), GPT-4 (OpenAI) and PaLM2 (Google), in automating migraine literature analysis by conducting sentiment analysis of migraine medications in clinical...

    Authors: Elyse Mackenzie, Roger Cheng and Pengfei Zhang
    Citation: BMC Neurology 2025 25:69
    Content type: Research Published on:

  46. Observational studies suggest an association between leukemia and stroke, but causality remains unclear. Certain leukemia types may increase stroke risk, but variations exist in stroke and mortality rates acro...

    Authors: Xiaoyao Yi, Jingrui Zhu, Xiang Zhang, Ning Huang and Yuan Cheng
    Citation: BMC Neurology 2025 25:68
    Content type: Research Published on:

  47. Brain processing of both somatosensation and emotion is altered in individuals with cerebral palsy. This paper aims at further exploring the interaction between the somatosensory system and affective processin...

    Authors: Inmaculada Riquelme, Álvaro Sabater-Gárriz, Samar M. Hatem, Elisabeth Martín-Jiménez and Pedro Montoya
    Citation: BMC Neurology 2025 25:67
    Content type: Research Published on:

  48. This study aims to evaluate the clinical and imaging risk factors for early neurological deterioration (END) and long-term neurological disability in patients with Single subcortical small infarction (SSSI).

    Authors: Xiao Feng, Meiherinisa Taiwakuli, Junyong Du, Wenhao Zhu and Shabei Xu
    Citation: BMC Neurology 2025 25:66
    Content type: Research Published on:

  49. Elderly individuals are susceptible to the accrual of White Matter Lesions (WMLs), a subcategory of cerebral small-vessel disease. WMLs are strongly linked to an increased risk of strokes, intracerebral hemorr...

    Authors: Dayuan Liu, Ning Li, Yubo Zhu, Qianhua Chen and Jigao Feng
    Citation: BMC Neurology 2025 25:65
    Content type: Research Published on:
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